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Exploring the State-of-the-Art in 4-chlorobenzyl chloride and APIs & Intermediates Sector Company: Tangshan Moneide Trading Co., Ltd. Official Website: https://www.moneidechem.com Phone: 86-315-8309571 Mobile: 15633399667 Email: sales@moneidechem.com Address: 2-7-523 Jidong Building Materials, Tangshan, Hebei 064000 China Product Overview: 4-Chlorobenzyl chloride Product Name: 4-Chlorobenzyl chloride Synonyms: 1-Chloro-4-(chloromethyl)-benzene; alpha,4-Dichlorotoluene; PCBC CAS No.: 104-83-6 Product URL: 4-chlorobenzyl chloride Sector: APIs and Intermediates Tangshan Moneide Trading Co., Ltd. is a prominent supplier in the APIs & Pharmaceutical Intermediates field, with a strong focus on 4-chlorobenzyl chloride . The compound serves as an indispensable intermediate for diverse pharmaceutical, agrochemical, and specialty chemical synthesis. Our decades of expertise and rigorous quality management have established us as a reliable partner for international customers requiring consistent quality, flexible logistics, and comprehensive regulatory support. The 4-chlorobenzyl chloride product adheres strictly to international quality standards, exceeding the requirements for pharmaceutical and fine chemical applications, including compliance with major pharmacopeias and environmental directives. Industry Trends in 4-Chlorobenzyl chloride and APIs & Intermediates The 4-chlorobenzyl chloride market has evolved alongside the accelerating growth of APIs and intermediates globally. According to Chemsynthesis and insights from Journal of Heterocyclic Chemistry , the push for greener synthesis, enhanced selectivity, and multi-functional API intermediates has driven ongoing innovations in process engineering and commercial production. Digitalization & Automation: Modern plant digitalization and advanced quality analytics are ensuring tighter specifications and batch consistency for 4-chlorobenzyl chloride used in GMP-critical settings (Source: PharmaTutor ). Green Chemistry: There is a marked shift toward employing sustainable catalysts and minimal-waste routes consistent with international REACH and EPA guidelines (Source: ACS Journals ). Integration with APIs Market: The demand for selective benzylation and halogenation intermediates is projected to grow at ~6% CAGR in API manufacturing through 2030 ( GrandViewResearch ). 4-Chlorobenzyl chloride Technical Parameters Table Parameter Typical Value Method Importance Chemical Formula C 7 H 6 Cl 2 Spectroscopy / Structural analysis Identification Molecular Weight 161.03 g/mol Theoretical / Calculation Molecular dosing Appearance Colorless to pale yellow liquid Visual Inspection Purity control Purity (by GC) ≥ 99.0% GC Analysis API/Intermediate synthesis Boiling Point 232 °C ASTM Method Process suitability Refractive Index (20°C) 1.5670 - 1.5690 ISO 5661-99 Optical testing Water Content <0.1% ISO Karl-Fischer Stability assurance CAS Number 104-83-6 Registry Reference ID Visualization: Technical Data & Trends ( 4-chlorobenzyl chloride ) Application Scenarios of 4-Chlorobenzyl chloride in Industry 4-chlorobenzyl chloride is central to the synthesis of numerous intermediates and active pharmaceutical ingredients. It is a preferred choice in: Pharmaceutical Manufacturing: Used as a benzylating agent in the preparation of antihistamines, antifungals, and cardiovascular drugs including clotrimazole , diclofenac , and selective antihypertensives ( PubMed Reference ). Agrochemical Synthesis: Key raw material for the development of novel pesticide and herbicide intermediates, boosting crop protection efficiency ( ScienceDirect Source ). Material Science: An intermediate for specialty polymers and UV-resistant additives, due to its halogen functionality and reactivity. Fine Chemicals: Reagent for the functionalization of aromatic systems, leveraged in dyes, perfumes, and stabilizer synthesis. As global manufacturing standards tighten, 4-chlorobenzyl chloride sourced from Tangshan Moneide Trading Co., Ltd. delivers precise batch-to-batch consistency vital to high-reliability applications. Expert FAQ: 4-Chlorobenzyl chloride Technical Terminologies Frequently Asked Technical Questions Q1: What is the structural formula of 4-chlorobenzyl chloride ? A: It is C 7 H 6 Cl 2 , with a chlorine atom at the para position on the benzene ring and a chloromethyl side chain. Q2: What is the typical purity specification for 4-chlorobenzyl chloride for API use? A: ≥99.0% (by GC analysis), with low byproducts and trace-level water content (<0.1%). Q3: Are there recommended storage conditions for this intermediate? A: Store in tightly sealed container111s under nitrogen at room temperature, away from light and moisture; optimal below 25°C. Refer to SDS for safety regulations. Q4: What typical certifications or compliance documents accompany 4-chlorobenzyl chloride ? A: COA, TDS, MSDS, and compliance with REACH, ISO 9001, and relevant GMP protocols. Q5: What are the major analytical methods for quality control? A: Gas Chromatography (GC), Nuclear Magnetic Resonance (NMR), HPLC impurity profiling, and Karl-Fischer titration for trace moisture. Q6: What is the HS code and global regulatory status? A: The HS code is 2903999090. It is classified as a hazardous chemical for transport, with REACH registration in the EU and TSCA listing in the US. Q7: Is 4-chlorobenzyl chloride handled under any specific environmental or safety regulations? A: Yes, it must be handled as a hazardous substance under local and international regulations, requiring controlled emissions, effluent handling and PPE for operators. Why Choose Tangshan Moneide Trading Co., Ltd. for 4-Chlorobenzyl chloride ? Extensive Experience: Decades of specialized operation in the field of APIs and intermediates production and supply. Quality Assurance: Rigorous multi-parameter testing and batch validation to meet international standards. Authority: Regular participation in international pharmaceutical expos and compliance with peer-reviewed processes ( ScienceDirect ). Technical Support: Responsive team for product selection, tech transfer, and regulatory documentation (Contact: sales@moneidechem.com , Tel: 86-315-8309571). Global Logistics: Experience in hazardous and temperature-sensitive deliveries, ensuring compliance and security at every stage. Inquire now for 4-chlorobenzyl chloride Conclusion & References 4-chlorobenzyl chloride stands at the intersection of high purity, regulatory compliance, and essential chemical reactivity—making it vital for APIs and intermediate synthesis. As the sector shifts towards greener, more efficient, and regulated processes, Tangshan Moneide Trading Co., Ltd. remains your authoritative partner. For in-depth product data, regulatory guidelines or global distribution, consult our 4-chlorobenzyl chloride product page or reach us at sales@moneidechem.com . References: Chemsynthesis – 4-Chlorobenzyl Chloride Data Sheet Journal of Heterocyclic Chemistry – Synthesis and Applications ACS Journals – Process Optimizations GrandViewResearch – API Market Analysis ScienceDirect – Pharmaceutical Intermediates Overview PubMed – Application of 4-chlorobenzyl chloride